Supporting Information ESD-Fold: RNA Folding Based on Simulated SHAPE Data

Abstract

Sn× PPV is a good approximation for MCC. Using elementary calculus, one can show that the values of MCC and F are less than or equal to the accuracy value. Since no significant differences are observed for this measures (see Table S1), we only used accuracy measure in our manuscript. The average values of accuracy, MCC and F for ESD-Fold (simulated SHAPE data) on fifteen RNA sequences over 100 trials are provided in Table S1.

Fatemeh Zare

Associate Professor

My research interests include bioinformatics, computational biology and artificial intelligence.