Article-Journal

EIA-CNDP: An exact iterative algorithm for critical node detection problem
In designing reliable and impermeable networks, the robustness of the network is evaluated against the removal and failure of the node …
A new hash function and its use in read mapping on genome
Mapping reads onto genomes is an indispensable step in sequencing data analysis. A widely used method to speed up mapping is to index a …
The assessment of histone acetylation marks in the vicinity of transcription factor binding sites in human CD4+ T cells using information theory methods
The genetic information encoded in structural genes is decoded by an intracellular process called gene expression. This mechanism is …
Draft genome sequence of Pseudomonas aeruginosa strain LMG 1272, an atypical white line reaction producer
The draft genome sequence of Pseudomonas aeruginosa LMG 1272, isolated from mushroom, is reported here. This strain triggers formation …
Transcription Factor Binding Sites Prediction Based on Histone Acetylations using Neural Networks
Histone acetylation is one of the most important epigenetic processes that regulate gene expression. In other words, chromatin exposes …
The assessment of efficient representation of drug features using deep learning for drug repositioning

Background

De novo drug discovery is a time-consuming and expensive process. Nowadays, drug repositioning is utilized as a common …

Disease gene prioritization using network topological analysis from a sequence based human functional linkage network
Sequencing large number of candidate disease genes which cause diseases in order to identify the relationship between them is an …
The effect of stochasticity on repair of DNA double strand breaks throughout non-homologous end joining pathway
DNA double strand breaks (DSBs) are the most lethal lesions of DNA induced by ionizing radiation, industrial chemicals and a wide …
Assessing the impact of exact reads on reducing the error rate of read mapping

Background

Nowadays, according to valuable resources of high-quality genome sequences, reference-based assembly methods with high …

S-FLN: A sequence-based hierarchical approach for functional linkage network construction
The functional linkage network (FLN) construction is a primary and important step in drug discovery and disease gene prioritization …