Associate Professor in National Institute of Genetic Engineering and Biotechnology
Head of the School of Biological Sciences, IPM – Institute for Research in Fundamental Sciences.
Faculty member of the medical genetics group, National Institute of Genetics and Biotechnology
Research interest(s):
Bioinformatics
Structural Biology
Systems Biology
Game theory
Recent Papers:
J. Salimi Sartakhti, M. H. Manshaei ,S. Bateni, M. Sadeghi, (2017) Evolutionary Emergence of Angiogenesis in Avascular Tumors using a Spatial Public Goods Game, PLoS ONE, Volume 12, Issue 4,.
Bahareh Khazaei, Javad Salimi Sartakhti, Mohammad Hossein Manshaei, Quanyan Zhu, Mehdi Sadeghi, Seyed Rasoul Mousavi (2017) HIV-1-infected T- cells dynamics and prognosis: An evolutionary game model, Computer Methods and Programs in Biomedicine, Volume 152, 1-14
Dorri F, Pezeshk , Sadeghi M (2017) Stochastic Cell Fate and Longevity of Offspring, Cell J.;19(3):343-351
zahra zamanzadeh; Mitra Ataei; Seyed Massood Nabavi; Ghasem Ahangaria; Mehdi Sadeghi; Mohammad Hosein Sanati, (2017) In Silico Perspectives on the Prediction of the PLP’s Epitopes involved in Multiple Sclerosis, Iranian J. Biotechnology, 15, 10-12
Fereshteh Chitsazian, Mehdi Sadeghi and Elahe Elahi (2017) Confident gene activity prediction based on single histone modification H2BK5ac in human cell lines, BMC Bioinformatics
Javad Salimi Sartakhtia, Mohammad Hossein Manshaeia, Mehdi Sadeghi (2017) MMP–TIMP interactions in cancer invasion: An evolutionary game-theoretical framework, Journal of Theoretical Biology, Volume 412, 17–26
Seyed Amir Malekpour, Hamid Pezeshk and Mehdi Sadeghi (2017) PSE-HMM: genome-wide CNV detection from NGS data using an HMM with Position- Specific Emission probabilities, BMC Bioinformatics
Samiie Pouragahi ; Mohammad Hossein Sanati ; Mehdi Sadeghi; and Marjan Nassiri-Asl (2016) Bioinformatics Approach for Pattern of Myelin-Specific Proteins and Related Human Disorders, Biotechnology and Health Sciences. 3(4)
Zahra Zamanzadeh, Ghasem Ahangari, Mitra Ataei, Samie Pouragahi, Seyed Massood Nabavi, Mehdi Sadeghi, Mohammad Hossein Sanati (2016) Association of New Putative Epitopes of Myelin Proteolipid Protein (58-74) with Pathogenesis of Multiple Sclerosis, Iranian Journal of Allergy, Asthma and Immunology, 15(5):394-402
Katayoun Samimi-Rad1, Ramin Rahimnia, Mahdi Sadeghi, Seyed Amir Malekpour, Mona Marzban, Maryam Keshvari, Seyed Jalal Kiani, Seyed-Moayed Alavian (2016) Epidemic History of Hepatitis C Virus among Patients with Inherited Bleeding Disorders in Iran, PLOS ONE, 11(9)
Seyed Amir Malekpour , Hamid Pezeshk , Mehdi Sadeghi (2016) MGP-HMM: Detecting genome-wide CNVs using an HMM for modeling mate pair insertion sizes and read counts, Mathematical Biosciences, 279 (2016) 53–62
Rahim Jafari, Mehdi Sadeghi, Mehdi Mirzaie (2016) Investigating the importance of Delaunay-based definition of atomic interactions in scoring of protein–protein docking results, Journal of Molecular Graphics and Modelling, 66, 108–114
Ali Sharifi-Zarchi, Mehdi Totonchi, Keynoush Khaloughi, Razieh Karamzadeh, Marcos J. Araúzo-Bravo, Hossein Baharvand, Ruzbeh Tusserkani, Hamid Pezeshk, Hamidreza Chitsaz and Mehdi Sadeghi (2015) Increased robustness of early embryogenesis through collective decision-making by key transcription factors, BMC Systems Biology, 9:23
Vajiheh Eskandari, Bagher Yakhchali, Mehdi Sadeghi, Ali Asghar Karkhane, Houra Ahmadi-Danesh1(2015) Efficient Cadmium Bioaccumulation by Displayed Hybrid CS3 Pili: Effect of Heavy Metal Binding Motif Insertion Site on Adsorption Capacity and Selectivity, Appl Biochem Biotechnol, 177(8):1729-41
Mohieddin Jafari, Mehdi Mirzaie and Mehdi Sadeghi (2015) Interlog protein network: an evolutionary benchmark of protein interaction networks for the evaluation of clustering algorithms, BMC Bioinformatics , 16:319
Pegah Khosravi, Vahid H Gazestani, Leila Pirhaji, Brian Law, Mehdi Sadeghi, Bahram Goliaei and Gary D Bader (2015) Inferring interaction type in gene regulatory networks using co‑expression data , Algorithms Mol Biol , 10:23
Mohammad-Hadi Foroughmand-Araabi, Bahram Goliaei, Kasra Alishahi, Mehdi Sadeghi, Sama Goliaei (2015) Codon usage and protein sequence pattern dependency in different organisms: a Bioinformatics approach, Journal of Bioinformatics and Computational Biology, Vol. 13, No. 2
Maryam PourkamaliAnaraki and Mehdi Sadeghi (2015) Honey bee-inspired algorithms for SNP haplotype reconstruction problem, Journal of Experimental & Theoretical Artificial Intelligence, May 12, 2015
Pegah Khosravi, Vahid H. Gazestani , Mohammad Akbarzadeh , Samira Mirkhalaf , Mehdi Sadeghi, Bahram Goliaei (2015) Comparative Analysis of Prostate Cancer Gene Regulatory Networks via Hub Type Variation, Avicenna J Med Biotech; 7(1): 8-15
M Norouzi, F Ramezani, A Khedive, M Sadeghi,(2014) Hepatitis B Virus Genotype D is the Only Genotype Circulating in Iranian Chronic Carriers, the Unique Pattern of Genotypic Homogeneity, Journal of Gastroenterology and Hepatology Research, 213(9): 1238-1243