Mehdi Sadeghi

Associate Professor in National Institute of Genetic Engineering and Biotechnology

Head of the School of Biological Sciences, IPM – Institute for Research in Fundamental Sciences.

Faculty member of the medical genetics group, National Institute of Genetics and Biotechnology

 

Research interest(s):

  • Bioinformatics
  • Structural Biology
  • Systems Biology
  • Game theory

 

Recent Papers:

  • J. Salimi Sartakhti, M. H. Manshaei ,S. Bateni, M. Sadeghi, (2017) Evolutionary Emergence of Angiogenesis in Avascular Tumors using a Spatial Public Goods Game, PLoS ONE, Volume 12, Issue 4,.
  • Bahareh Khazaei, Javad Salimi Sartakhti, Mohammad Hossein Manshaei, Quanyan Zhu, Mehdi Sadeghi, Seyed Rasoul Mousavi (2017) HIV-1-infected T- cells dynamics and prognosis: An evolutionary game model, Computer Methods and Programs in Biomedicine, Volume 152, 1-14
  • Dorri F, Pezeshk , Sadeghi M (2017) Stochastic Cell Fate and Longevity of Offspring, Cell J.;19(3):343-351
  • zahra zamanzadeh; Mitra Ataei; Seyed Massood Nabavi; Ghasem Ahangaria; Mehdi Sadeghi; Mohammad Hosein Sanati, (2017) In Silico Perspectives on the Prediction of the PLP’s Epitopes involved in Multiple Sclerosis, Iranian J. Biotechnology, 15, 10-12
  • Fereshteh Chitsazian, Mehdi Sadeghi and Elahe Elahi (2017) Confident gene activity prediction based on single histone modification H2BK5ac in human cell lines, BMC Bioinformatics
  • Javad Salimi Sartakhtia, Mohammad Hossein Manshaeia, Mehdi Sadeghi (2017) MMP–TIMP interactions in cancer invasion: An evolutionary game-theoretical framework, Journal of Theoretical Biology, Volume 412, 17–26
  • Seyed Amir Malekpour, Hamid Pezeshk and Mehdi Sadeghi (2017) PSE-HMM: genome-wide CNV detection from NGS data using an HMM with Position- Specific Emission probabilities, BMC Bioinformatics
  • Samiie Pouragahi ; Mohammad Hossein Sanati ; Mehdi Sadeghi; and Marjan Nassiri-Asl (2016) Bioinformatics Approach for Pattern of Myelin-Specific Proteins and Related Human Disorders, Biotechnology and Health Sciences. 3(4)
  • Zahra Zamanzadeh, Ghasem Ahangari, Mitra Ataei, Samie Pouragahi, Seyed Massood Nabavi, Mehdi Sadeghi, Mohammad Hossein Sanati (2016) Association of New Putative Epitopes of Myelin Proteolipid Protein (58-74) with Pathogenesis of Multiple Sclerosis, Iranian Journal of Allergy, Asthma and Immunology, 15(5):394-402
  • Katayoun Samimi-Rad1, Ramin Rahimnia, Mahdi Sadeghi, Seyed Amir Malekpour, Mona Marzban, Maryam Keshvari, Seyed Jalal Kiani, Seyed-Moayed Alavian (2016) Epidemic History of Hepatitis C Virus among Patients with Inherited Bleeding Disorders in Iran, PLOS ONE, 11(9)
  • Seyed Amir Malekpour , Hamid Pezeshk , Mehdi Sadeghi (2016) MGP-HMM: Detecting genome-wide CNVs using an HMM for modeling mate pair insertion sizes and read counts, Mathematical Biosciences, 279 (2016) 53–62
  • Rahim Jafari, Mehdi Sadeghi, Mehdi Mirzaie (2016) Investigating the importance of Delaunay-based definition of atomic interactions in scoring of protein–protein docking results, Journal of Molecular Graphics and Modelling, 66, 108–114
  • Ali Sharifi-Zarchi, Mehdi Totonchi, Keynoush Khaloughi, Razieh Karamzadeh, Marcos J. Araúzo-Bravo, Hossein Baharvand, Ruzbeh Tusserkani, Hamid Pezeshk, Hamidreza Chitsaz and Mehdi Sadeghi (2015) Increased robustness of early embryogenesis through collective decision-making by key transcription factors, BMC Systems Biology, 9:23
  • Vajiheh Eskandari, Bagher Yakhchali, Mehdi Sadeghi, Ali Asghar Karkhane, Houra Ahmadi-Danesh1(2015) Efficient Cadmium Bioaccumulation by Displayed Hybrid CS3 Pili: Effect of Heavy Metal Binding Motif Insertion Site on Adsorption Capacity and Selectivity, Appl Biochem Biotechnol, 177(8):1729-41
  • Mohieddin Jafari, Mehdi Mirzaie and Mehdi Sadeghi (2015) Interlog protein network: an evolutionary benchmark of protein interaction networks for the evaluation of clustering algorithms, BMC Bioinformatics , 16:319
  • Pegah Khosravi, Vahid H Gazestani, Leila Pirhaji, Brian Law, Mehdi Sadeghi, Bahram Goliaei and Gary D Bader (2015) Inferring interaction type in gene regulatory networks using co‑expression data , Algorithms Mol Biol , 10:23
  • Mohammad-Hadi Foroughmand-Araabi, Bahram Goliaei, Kasra Alishahi, Mehdi Sadeghi, Sama Goliaei (2015) Codon usage and protein sequence pattern dependency in different organisms: a Bioinformatics approach, Journal of Bioinformatics and Computational Biology, Vol. 13, No. 2
  • Maryam PourkamaliAnaraki and Mehdi Sadeghi (2015) Honey bee-inspired algorithms for SNP haplotype reconstruction problem, Journal of Experimental & Theoretical Artificial Intelligence, May 12, 2015
  • Pegah Khosravi, Vahid H. Gazestani , Mohammad Akbarzadeh , Samira Mirkhalaf , Mehdi Sadeghi, Bahram Goliaei (2015) Comparative Analysis of Prostate Cancer Gene Regulatory Networks via Hub Type Variation, Avicenna J Med Biotech; 7(1): 8-15
  • M Norouzi, F Ramezani, A Khedive, M Sadeghi,(2014) Hepatitis B Virus Genotype D is the Only Genotype Circulating in Iranian Chronic Carriers, the Unique Pattern of Genotypic Homogeneity, Journal of Gastroenterology and Hepatology Research, 213(9): 1238-1243
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