Mehdi Sadeghi

Associate professor at NIGEB & IPM

Associate professor of cell and molecular biology at National Institute of Genetic Engineering and Biotechnology (NIGEB)

Head of School of Biological Sciences, IPM Institute For Research In Fundamental Sciences

 

Research interests:

  • Bioinformatics
  • Structural Biology
  • Systems Biology
  • Game theory

 

Recent Papers:

  • Sadeghi, M., Barzegar, A. “Precision medicine insight into primary prostate tumor through transcriptomic data and an integrated systems biology approach“. Meta Gene. 26: 100787 (2020).
  • Malekpour, S. A., Alizad-Rahvar, A. R., Sadeghi, M. “LogicNet: probabilistic continuous logics in reconstructing gene regulatory networks“. BMC bioinformatics. 21(1): 1-21 (2020).
  • Pashabayg, C. R., Momenifar, N., Malekpour, S. A., Sadeghi, M., Foroushani, A. R., et al. “Phylogenetic and phylodynamic study of Human T-cell lymphotropic virus Type 1 (HTLV-1) in Iran“. Infection, Genetics and Evolution. 85: 104426 (2020).
  • Bayat, R., Sadeghi, M., Aref, M. R. “Modeling gene regulatory networks: Classical models, optimal perturbation for identification of network“. Signal and Data Processing. 17(2): 112-101 (2020).
  • Ejlali, N., Pezeshk, H., Chaubey, Y. P., Sadeghi, M., Ebrahimi, A. et al. “Parrondo’s paradox for games with three players and its potential application in combination therapy for type II diabetes“. Physica A: Statistical Mechanics and its Applications. 124707 (2020).
  • Safdari, H., Kalirad, A., Picioreanu, C., Tusserkani, R., Goliaei, B., Sadeghi, M. “Noise-driven cell differentiation and the emergence of spatiotemporal patterns“. Plos one. 15(4): e0232060 (2020).
  • Vafadar, S., Kavousi, K., Safdari, H., Kalira, A., Sadeghi, M. “From indication to decision: A hierarchical approach to model the chemotactic behavior of Escherichia coli“. Journal of Theoretical Biology. 110253 (2020).
  • Salari, F., Zare Mirakabad, F., Sadeghi, M. “A new hash function and its use in read mapping on genome“. AUT Journal of Mathematics and Computing. (2020).
  • Alizad-Rahvar, A. R., Vafadar, S., Totonchi, M., Sadeghi, M. “False-Negative Mitigation in Group Testing for COVID-19 Screening“. medRxiv. (2020).
  • Khorasani, N., Sadeghi, M., Nowzari-Dalini, A. “A Computational Model of Stem Cell Molecular Mechanism to Maintain Tissue Homeostasis“. bioRxiv. (2020).
  • Salehi, N., Attaran, B., Eskini, N., Esmaeili, M., Sharifirad, A., Sadeghi, M. et al. “New insights into resistance of Helicobacter pylori against third‐ and fourth‐generation fluoroquinolones: A molecular docking study of prevalent GyrA mutations“. Helicobacter. 24(5): e12628 (2019).
  • Shahdoust, M., Mahjub, H., Pezeshk, H., Sadeghi, M. “A Network-based Comparison between Molecular Apocrine Breast Cancer Tumor and Basal and Luminal Tumors by Joint Graphical Lasso“. IEEE/ACM Transactions on Computational Biology and Bioinformatics. (2019).
  • Kalirad, A., Safdari, H., Sadeghi, M. “The lottery of spermatogenesis“. bioRxiv. 646422 (2019).
  • Safdari, H., Sadeghi, M., Kalirad, A. “Making ATP fast and slow: do yeasts play a mixed strategy to metabolise glucose?“. bioRxiv. 540757 (2019).
  • Mohseni-Salehi, F. S., Zare-Mirakabad, F., Ghafouri-Fard, S., Sadeghi, M. “The effect of stochasticity on repair of DNA double strand breaks throughout non-homologous end joining pathway“. Mathematical Medicine and Biology: A Journal of the IMA. 35(4): 517-539 (2018).
  • Salari, F., Zare-Mirakabad, F., Sadeghi, M., Rokni-Zadeh, H. “Assessing the impact of exact reads on reducing the error rate of read mapping“. BMC bioinformatics. 19(1): 406 (2018).
  • Alizad-Rahvar, A. R., Sadeghi, M. “Ambiguity in logic-based models of gene regulatory networks: An integrative multi-perturbation analysis“. PloS one. 13(11): e0206976 (2018).

 

 

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